The IL-1a Antibody from MyBioSource.com is a Mouse Monoclonal antibody to IL-1, IL-1 alpha, IL1, IL1 alpha, IL1-ALPHA, IL1A, Interleukin 1 alpha, and Miscellaneous. This antibody recognizes Human antigen. The IL-1a Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
Background: Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease